Atypical fibroxanthoma (AFX) is a dermal spindle-cell tumour that typically occurs on the head and neck of sun damaged older people. The tumour-like growth should be considered a type of skin cancer but it may behave in a benign fashion. A rare type of atypical fibroxanthoma occurs in younger patients on parts of the body that are not normally overexposed to the sun.

Atypical fibroxanthoma (AFX) is a nodular dermal ulcerative lesion with a favorable prognosis. AFX most commonly occurs on sun-exposed skin in elderly individuals. AFX is characterized by its association with ultraviolet radiation, not only from a clinical aspect, but also from a molecular aspect. Making a diagnosis of AFX is challenging, and it is important to differentiate it from squamous

One such tumor is the atypical fibroxanthoma (AFX), which is widely considered as a "pseudomalignant" tumor. It is derived 2013-03-26 Atypical fibroxanthoma (AFX) is a nodular dermal ulcerative lesion with a favorable prognosis. AFX most commonly occurs on sun-exposed skin in elderly individuals. has an excellent prognosis, b ut long-term follow-up is recommended due to the potential for aggr essive behavior. Atypical fibroxanthoma (AFX) is a rare primary mesenchymal skin tumor of Atypical fibroxanthoma of the skin is a low-grade malignancy related to malignant fibrous histiocytoma, which it resembles histologically.: 613 Atypical fibroxanthoma (AFX) is an uncommon cutaneous neoplasm that usually presents as a rapidly-growing nodule in sun-exposed sites in elderly patients. Despite its highly atypical histological appearance it is almost always associated with innocuous clinical behaviour. AFX is now generally regarded as the superficial counterpart of undifferentiated pleomorphic sarcoma (so-called malignant Atypical fibroxanthoma is a type of skin cancer that typically occurs on the head and neck of older people who have had lots of sun damage.

Atypical fibroxanthoma prognosis

Fortunately, atypical fibroxanthoma rarely metastasizes and recurs in only 6% to 10% of cases 6). 2020-10-14 Atypical Fibroxanthoma. Atypical fibroxanthoma is a malignant skin tumor with histologic features similar to those of undifferentiated pleomorphic sarcoma, but lacking its more aggressive behavior.

of the mass as they could in surgery, but because it was so close to her spine, she was left with positive margins and required further treatment to get the rest.

2020-10-14 · Atypical fibroxanthoma (AFX) is a tumor that occurs primarily in older individuals after the skin of the head and neck has been damaged significantly by sun exposure and/or therapeutic radiation. Atypical Fibroxanthoma (Concept Id: C0346053) An intermediate cutaneous mesenchymal neoplasm of uncertain differentiation, usually affecting the actinic-damaged skin of the elderly. The tumor presents as a single cutaneous nodule which is often ulcerated. Atypical Fibroxanthoma of the skin (AFX) is an uncommon tumor of sun-exposed areas of elderly white men, most commonly on the scalp and ears.

Atypical fibroxanthoma (AFX) is a nodular dermal ulcerative lesion with a favorable prognosis. AFX most commonly occurs on sun-exposed skin in elderly individuals.

Atypical fibroxanthoma of skin: an electron microscope study. Pathology. 1975(3); 7:173-7. Woyke S, Domagala W, Olszewski W, Korabiec M. Pseudosarcoma of the skin: an electron microscopic study and comparison with the fine structure of spindle-cell variant of squamous carcinoma. Atypical fibroxanthoma is a low-grade sarcoma of the skin. (See also Overview of Skin Cancer.) Atypical fibroxanthomas are rare among nonmelanoma skin cancers. They most commonly occur on the head and neck of older patients.

It resembles squamous cell carcinoma or basal cell carcinoma because of the presence of a pink papule or erosion. It is usually diagnosed only after biopsy. Tumors involving the dermis and superficial fat are termed atypical fibroxanthoma and rarely metastasize. AFX is one of the more recognizable skin cancers that can affect the body. It is characterized by the sudden development of a red or pink bump, nodule, or dome shaped ulcer.
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Kram A, Stańczyk J, Woyke S Pol J Pathol 2003;54(4):267-71. PMID: 14998296 BACKGROUND: Atypical fibroxanthoma (AFX) and malignant fibrous histiocytoma (MFH) are tumours of the fibrous tissue.

Diagnosis is made by immunohistochemistry. AFX generally has a good prognosis. Metastasis is a rare event.
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Atypical fibroxanthoma of skin: an electron microscope study. Pathology. 1975(3); 7:173-7. Woyke S, Domagala W, Olszewski W, Korabiec M. Pseudosarcoma of the skin: an electron microscopic study and comparison with the fine structure of spindle-cell variant of squamous carcinoma.

The lumps may be pink or red in colour. They can be ulcerated or crusted.

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Feb 15, 2016 Atypical fibroxanthoma (AFX) is a rare skin tumor that characteristically follows a benign clinical course despite its ominous and malignant

This chapter is set out as follows: Atypical Fibroxanthoma (Concept Id: C0346053) An intermediate cutaneous mesenchymal neoplasm of uncertain differentiation, usually affecting the actinic-damaged skin of the elderly. The tumor presents as a single cutaneous nodule which is often ulcerated. 2017-12-08 2010-09-01 Atypical fibroxanthoma (AFX): Four cases Deba P Sarma, MD., Omaha 1. Atypical fibroxanthoma (AFX), F 49 R chest histologically, the prognosis is excellent following conservative excision. Larger tumors (>2 cm) which extensively invade subcutaneous tissue such as fascia or muscle, or show The term atypical fibroxanthoma (AFX) was used in 1961 by Helwig for indicate a typically nodular ulcerative lesion arising from the sun-exposed skin of the head and neck. Rarely AFX has been described in young and in areas without evidence of actinic damage.